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Trigeminal Neuralgia
Trigeminal neuralgia (TN), also known as tic douloureux, is a chronic pain condition that affects the trigeminal nerve, which is responsible for carrying sensation from the face to the brain. Here’s an overview:
Symptoms:
- Intense Pain: Sudden, severe, stabbing or electric shock-like pain in the face.
- Location: Typically affects one side of the face, often the lower face and jaw, but can also affect the area around the nose and above the eye.
- Triggers: Pain can be triggered by mild stimulation of the face such as eating, talking, brushing teeth, shaving, or even a breeze.
- Duration: Attacks can last from a few seconds to several minutes and can occur in rapid succession. Periods of remission (pain-free intervals) can occur but often decrease over time.
Causes:
- Nerve Compression: Most commonly caused by a blood vessel pressing on the trigeminal nerve as it exits the brainstem.
- Multiple Sclerosis (MS): Demyelination of the trigeminal nerve can cause TN in patients with MS.
- Tumors: Rarely, tumors compressing the trigeminal nerve can cause TN.
- Injury: Facial or surgical trauma can damage the trigeminal nerve.
Diagnosis:
- Clinical Evaluation: Diagnosis is primarily based on the patient’s description of symptoms and medical history.
- Imaging Tests: MRI scans can identify if a blood vessel is compressing the nerve or if there are other structural causes like a tumor.
Treatment:
Medications:
- Anticonvulsants: Drugs such as carbamazepine and oxcarbazepine are often the first line of treatment.
- Muscle Relaxants: Baclofen can be used alone or in combination with anticonvulsants.
- Tricyclic Antidepressants: Low doses of amitriptyline or nortriptyline may be effective for some patients.
Surgical Options:
- Microvascular Decompression (MVD): Relieves the pressure on the trigeminal nerve by moving or removing the blood vessel causing the compression.
- Gamma Knife Radiosurgery: Focused radiation to damage the trigeminal nerve and reduce pain signals.
- Rhizotomy: Various techniques (balloon compression, glycerol injection, radiofrequency thermal lesioning) to selectively damage the nerve fibers to block pain.

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